Showing posts with label steroids. Show all posts
Showing posts with label steroids. Show all posts

Friday, March 27, 2015

What Are the Real Problems Associated with Trenbolone Use?

A key thing to consider with trenbolone is dosage.
Back in 1998 when the 50 mg/day trenbolone dosage was nearly-unheard-of and was very contrary to the published advice of the time. The books of the era advised using no more than 1 Parabolan ampule per week, as the steroid was so strong: the amount of trenbolone contained in such an ampule is the same as 50 mg of trenbolone acetate. Among the hardcore who would not be limited by the advice of the day, Finaject was sometimes used at 50 mg two or three times a week. Daily use of such an amount of trenbolone was just not an accepted practice at all in the United States.

However, in Europe daily injection of Parabolan was an accepted practice among the serious and experienced. Hence, 50 mg/day trenbolone acetate. A 50 mg/day was perceived then as a very high level, and it actually is a pretty high level of drug. Trenbolone should be thought of as about 3 times more potent (strength per milligram) than most anabolic steroids; on that basis, 50 mg/day is “like” about 150 mg/day of another steroid. It’s not a low dose. No surprise if it has its own significant side effects.

These days, however, largely from 75 mg/mL and 100 mg/mL concentrations being available, doses have popularly risen to 75 or 100 mg/day. People always realize how high such doses really are. Let alone 150 mg/day.

It’s not surprising that some experience adverse side effects from such increased doses.

In terms of side effects the great majority do well with 50 mg/day, a few require dosage to be as little as about 30-35 mg/day, and an even smaller number just really don’t do well with trenbolone at all, principally for the reasons you say, and with night sweats as another potential reason.

And then there are those also who can use 75-100 mg/day or more without real problem.

For behavior, there is exercise of the will. For some this is effective; for others, not very effective. It has to be personally evaluated. For sleep problems, if ordinarily needing no sleep-aiding supplement, then for example a well-formulated product can sometimes be enough to make the difference.

Many bodybuilders found real benefit with Mod GRF 1-29. It doesn’t promote falling asleep, but does promote deep-cycle sleep once sleep has begun. It’s not a necessity but can be a help.

Friday, December 5, 2014

Can Steroids Cause Hair Loss?

Genetics play an important role in the sports world. In body building genetics plays an even more important part. For many, their genetic predisposition to gain lean muscle easily will give them an obvious advantage of the more thinly framed. For others, it’s their ability to loss body fat without losing muscle that will help them gain the edge. With this focus on genetics, it’s to be reminded of other genetic factors that come into play. Hair loss is one of them. Not everyone is affected by hair loss. Some men will start showing signs of baldness in their late twenties; others will keep their well into their twilight years.

If members of your family are prone to male pattern baldness, it is more than likely that you also have the genetic markers. Anabolic steroids will only serve to speed up this process. An understanding of what is in anabolic steroids and how your body processes will help you to understand why it is that you should avoid using steroids.

DHT

DHT (Dihydrotestosterone) is a substance in your body that binds to receptors in hair follicles causing a thinning of the hairline. DHT is made when testosterone is converted by an enzyme called 5AR (5 Alpha reductase). If you have a genetic disposition for male pattern baldness then you already have the necessary substances flowing through your body. Testosterone and 5AR. Whats worse is that some steroids don’t even have to be converted. Anadrol and Winstrol are derived from DHT. This means that they don’t have to be converted to affect your hairline. They are able to bind directly to the hair follicles. There are several other steroids on the market that interact differently with your body, almost all of them having a negative effect on your hairline.

DHT can also have cause another change in your body chemistry. DHT can actually signal the body’s immune system to attack hair follicles. So now, not only is your body chemistry creating a hostile growth environment for hair, but it is also telling your body to attack hair follicles.

 Will it grow back?

Most likely some of you are reading this because you noticed a few too many hairs were lining the sink this morning. The important thing is that you realize this. If you are cycling steroids and your hair starts falling out, it means your hair follicles are sensitive to androgens. Unless you’ve decided to embrace baldness, you need to stop immediately. If you have a family history of male pattern baldness, you have probably activated it prematurely. At this point your only hope is to slow its onset. You’re next step is to visit an endocrinologist. Only a qualified medical professional can diagnose and treat your condition.

In the interest of full disclosure, it is difficult if not impossible to grow hair back that was lost due to high levels of DHT. Your goal at this point is to dramatically slow down the process.

 Body Image

Think about why most people start body building in the first place. Chances are it is to fix some body image issues. What were your reasons? Whatever they may be, at the root of it is a desire to be respected. It takes a lot of motivation and determination to reach your goals. Is the risk of steroids unwanted side effects worth it? For some the answer is yes.

Do steroids cause hair loss? No but if you have any genetic disposition to losing your hair early or if anyone in your family suffers from male pattern baldness, your choice to use steroids could very well speed it up. Compounding this danger is the fact that some people realize they could lose their hair. So in an effort to protect their hairline, they use solutions like Finasteride, Nizoral, Minoxidil thinking that these alone will protect their hair. The truth is they are only going to help slow things down. Once your the genes that cause baldness have been turned on, their damage is permanent. Baldness is not simply a symptom of a hormone imbalance. Male pattern baldness is a result. Results like baldness can be permanent. The best way to avoid hair loss from steroid use is to avoid steroids from the beginning.

Choosing a natural approach to body building may be hard. If you people want to get the results from steroids only then it seems impossible. You have to change your mind set. The benefits of a long term change in lifestyle will far outweigh any short term gains from steroids.

Friday, October 25, 2013

Do Steroids Make Your Penis Shrink Or Do Steroids Make Your Penis Grow?

It’s a big concern for all men who are thinking of using steroids or andro prohormones…

In countless locker rooms across America a conversation very similar to this has transpired: Joe Sixpack: “so will using steroids make my penis shrink?” John Sixpack: “I don’t think it’s the penis that shrinks it’s the balls, right?” Jim Sixpack: “I don’t know, they always make fun of the buff guy in movies saying he has no dick because he used steroids.” And so the questions linger and get bantered around over and over again. Many of you may be considering using steroids or legal anabolics like prohormones and have the same questions as the guys were asking above and so, we will address them here in this article.
Will steroids shrink my penis?

Steroids do not impact the male’s penis unless he is still on the growing stage of his development. Some say that the growth stage is basically over at 18 and other at 21. Either way, it’s a pretty safe bet that if you are over 21 you should be good to go. This is why the common advice out there is to not use anabolic steroids unless you are over 21. So the short answer is, if you are over 21 and not growing anabolic steroids will have no effects on your penis size.

Just for discussion sake, if you were under 18 and still growing depending on the type of steroids you used you could either potentially make your penis larger or smaller. This can never be recommended however. There is some good evidence however that using creatine is safe for all ages and could shift your body to a more DHT laden anabolic state that would make a good environment biologically for growing a bigger penis.
Will steroids make my testicles shrink?

The short answer is yes, that most anabolic/androgenic steroids will cause temporary, key word here is temporary, testicle shrinkage as long as they are used in a safe and effective way. Basically, when a person uses steroids they are introducing a hormone from outside their body, at levels higher than their body could ever produce, and so the body signals itself to slow down making its own hormones because there is already plenty to go around. This leads to smaller testicles while “on” cycle.

Once you go off the steroids or prohormones normal hormone production within the body recovers and testicle size goes back to normal. Post Cycle Therapy can speed this recovery process along.

There are no scientific ways to induce lasting penis growth at this time without surgery

Sorry to say but there is no magic pill or machine that can make your penis grow larger than it already is if you are over 21 and done growing. Perhaps it’s time to focus on using what you have with excellence rather than trying to make it bigger.

If you’re looking for a safe and effective prohormone stack with built-in post-cycle therapy, scroll down and see our top recommendations. Your penis may not get any bigger, but your muscles will.

Thursday, October 3, 2013

How Steroids May Be Beating Your Prostate Into Dysfunction

Ask any teenager the effects of steroids, and his mainstream media brainwashing will likely cause him to respond with the three most commonly cited side effects. The first side effect mentioned will likely be liver damage. We all know that injectables don't affect liver function much, and even orals cause rises to levels, which are still typically acceptable.

In most healthy males, only long-term abuse of anabolic steroids leads to liver damage. The second side effect he'll recall is acne. While this is unavoidable as skin receptors do react to anabolics, many topical and oral medications exist which can mostly alleviate this problem. This third side effect - harder to determine without a very invasive examination - is prostate damage. Do steroids really cause prostate damage?

For decades, scientists have cited prostate enlargement as a side effect of steroid use. The media has run with this assumption and declared steroids cause prostate cancer. In reality, this is not the case. It is correct that the prostate enlarges when androgens are present in the body. DHT or Testosterone inserted into the body will bind to receptors in the prostate, and new growth will occur as a result. However, once the bodybuilder stops the cycle, the prostate returns to regular size.

There are only two periods of life in which the prostate is enlarged. The first occurs during puberty when the body is producing obscene amounts of testosterone. After that, the prostate remains a constant size for the next 25 to 40 years. As men reach their 40's and 50's, prostate growth does begin again in all men. For men in this position, Dutasteride or Finasteride can help with prostate size reduction as well.

Therefore the average steroid user in his 20s or 30s will experience an enlargement of the prostate, but it will typically be nothing to become alarmed about. This does present an interesting set of risks for steroid users age 40 and above. Their prostate may begin growing naturally. Coupled with anabolic steroid use, real problems can occur.

If you are over age 40 and using steroids, annual prostate exams are essential. Males under the age of 22 should not use steroids. Not only because their prostate may be enlarged, but also because their bodies are already producing levels of testosterone sufficient for muscle growth. Toying with levels at this age can lead to a lifetime requirement of hormone replacement therapy.

Friday, August 30, 2013

Can Testosterone Replacement Therapy Cause Cancer?

One of the pressing questions men ask when faced with the possibility of starting testosterone hormone therapy is, “Can testosterone replacement therapy cause cancer?” Up until recently, this question would likely have been answered by most doctors with a resounding “yes.”

However, a great deal of research has been done to determine whether the “yes” response to the question about testosterone therapy and prostate cancer is accurate, and based on accumulating evidence, it appears the answer is “no.” One compelling reason for the “no” response can be attributed to the comprehensive investigative work done by Abraham Morganthaler, MD, FACS, author of Testosterone for Life, who evaluated the original work by urologist Charles Higgins in the 1940s, research that led to the misconception that taking testosterone can cause prostate cancer.

Morganthaler discovered that this idea arose out of one case study involving one patient. In other words, the fear that testosterone therapy can cause prostate cancer was based on nothing. In fact, in recent years there have been many studies that dispel the myth that testosterone replacement therapy causes prostate cancer or has a significant negative impact on the prostate. For example:

    A Beth Israel Deaconess Medical Center review of 72 studies (Rhoden 2004) found “no compelling evidence that testosterone replacement therapy increases the incidence of prostate cancer.”
    A report by The Prostate Cancer Center Hamburg-Eppendorf in Germany. (Isbarn 2009) stated “the available research strongly suggested that testosterone therapy neither increases the risk of prostate cancer in normal men nor causes a recurrence of the cancer in men who have been treated successfully for prostate cancer.”
    In a study of 57 men who received testosterone supplementation for an average of 36 months after prostatectomy surgery, although mean testosterone levels rose in all the men before testosterone therapy, there was no increase in PSA values after testosterone therapy started. So, testosterone replacement therapy caused hormone levels to rise, PSA values to remain the same, and symptoms to be relieved. Baylor College of Medicine study (Khera 2009)
    A study conducted within the ongoing Osteoporotic Fractures in Men cohort looked at the association between testosterone, estradiol, estrone, and sex hormone-binding globulin and prostate cancer. Only estrone was strongly related to an increased risk of prostate cancer. University of California, San Francisco.
    In a landmark study reported in 2006, men who had low testosterone levels were given testosterone injections or placebo every two weeks for six months. Before and throughout the study, the investigators took measurements of testosterone and DHT from both blood samples and the prostate itself. The researchers found that although blood concentrations of testosterone and DHT rose substantially in men who were given hormone replacement therapy, the concentration of testosterone and DHT did not change at all in the prostate gland. In addition, testosterone therapy had no effect on biochemical markers of prostate cell growth. Therefore, the authors noted that while testosterone replacement therapy normalized blood levels of testosterone, treatment did not affect prostate tissue or prostate cell functions. According to Morganthaler, “it is as if once the prostate has been exposed to enough testosterone, any additional testosterone is treated as excess and does not accumulate in the prostate.” To state it another way, he said “we say the prostate has been saturated with regard to testosterone.”

According to a Johns Hopkins Prostate Disorders Special Report, “Testosterone-Replacement Therapy: Does It Increase Prostate Cancer Risk?” the jury is still out on whether testosterone replacement therapy is safe when men take it for a prolonged time. Morganthaler would take that a step further, as he has noted that “The relationship of testosterone to prostate cancer has undergone a significant reevaluation, and all recent evidence has reinforced the position that testosterone therapy is safe for the prostate.”

In addition, if you already have prostate cancer, the concern has been that taking testosterone could make the cancer progress faster, or that the hormone could promote tumor growth. These worries are the reasons why some doctors will not prescribe testosterone therapy for men who have a history of prostate cancer.

Tuesday, June 18, 2013

How Steroids May Be Beating Your Prostate Into Dysfunction

Ask any teenager the effects of steroids, and his mainstream media brainwashing will likely cause him to respond with the three most commonly cited side effects. The first side effect mentioned will likely be liver damage. We all know that injectables don't affect liver function much, and even orals cause rises to levels, which are still typically acceptable.

In most healthy males, only long-term abuse of steroids leads to liver damage. The second side effect he'll recall is acne. While this is unavoidable as skin receptors do react to anabolic steroids, many topical and oral medications exist which can mostly alleviate this problem. This third side effect - harder to determine without a very invasive examination - is prostate damage. Do steroids really cause prostate damage?

For decades, scientists have cited prostate enlargement as a side effect of steroid use. The media has run with this assumption and declared steroids cause prostate cancer. In reality, this is not the case. It is correct that the prostate enlarges when androgens are present in the body. DHT or Testosterone inserted into the body will bind to receptors in the prostate, and new growth will occur as a result. However, once the bodybuilder stops the cycle, the prostate returns to regular size.

There are only two periods of life in which the prostate is enlarged. The first occurs during puberty when the body is producing obscene amounts of testosterone. After that, the prostate remains a constant size for the next 25 to 40 years. As men reach their 40's and 50's, prostate growth does begin again in all men. For men in this position, Dutasteride or Finasteride can help with prostate size reduction as well.

Therefore the average steroid user in his 20s or 30s will experience an enlargement of the prostate, but it will typically be nothing to become alarmed about. This does present an interesting set of risks for steroid users age 40 and above. Their prostate may begin growing naturally. Coupled with anabolic steroid use, real problems can occur.

If you are over age 40 and using steroids, annual prostate exams are essential. Males under the age of 22 should not use steroids. Not only because their prostate may be enlarged, but also because their bodies are already producing levels of testosterone sufficient for muscle growth. Toying with levels at this age can lead to a lifetime requirement of hormone replacement therapy. 

Thursday, May 2, 2013

Treating Pain and Other Symptoms

If prostate cancer or its therapy is causing pain, there's no need to suffer in silence. Effective treatments are available.

Pain Medicines
Pain medicines work very well. When the drugs are being used as directed to treat cancer pain, you do not need to worry about addiction or dependence. You may have symptoms like tiredness and itching, but these usually go away after you get used to the medicine. Constipation is the most common problem, but there are things you can do to prevent this. Side effects can often be managed by changing the dosage or by adding other medicines.

Bisphosphonates
This is a group of drugs that can help relieve bone pain caused by cancer that has spread to the bones. They may also slow the growth of the cancer cells and strengthen bones in men who are getting hormone treatment.

Bisphosphonates can cause side effects, such as flu-like symptoms and bone pain. Some men have had a very rare, but distressing side effect from these drugs. They have pain in the jaw and their doctors find that part of the jaw bone has died. This can lead to loss of teeth or infections of the jaw bone. Doctors don't know why some people develop these jaw problems or how to prevent them. So far, the only treatment has been to stop the bisphosphonate treatment. Some cancer doctors recommend that patients have a dental check-up and have any tooth or jaw problems treated before they start taking bisphosphonates.

Steroids
Steroids can relieve bone pain and increase appetite for some men.

Radiation Therapy
While radiation therapy can be used as the main treatment for prostate cancer, it can also be used to treat bone pain caused by cancer that has spread to the bone.

Drugs called radiopharmaceuticals are also used for this purpose. This is a group of drugs that have radioactive elements. They are given into a vein. They settle in areas of bones that contain cancer and the radioactive part kills the cancer cells there. About 8 out of 10 prostate cancer patients with bone pain are helped by this treatment. The main side effect is a lowering of blood cell counts. This could increase your risk of getting an infection or bleeding easily.

Monday, February 27, 2012

Steroid Effects on Prostate Gland


Prostate gland is sensitive to different hormonal actions and is able to absorb selectively male and female sex hormones. Here binding of androgens occurs in androgen-dependent part of prostate gland and binding of estrogens occurs in estrogen-dependent part.

Androgens in prostate gland are not accumulated, instead they are rapidly transformed. Estrogens remain mainly unchanged. Steroid hormones of all classes are transported via blood plasma in form of protein complex. Blood contains estradiol. It binds beta globulin and is able to bind steroids having hydroxyl. Unlike peptidic hormones, which act on level of external cell membranes, steroid hormones enter cells and do bind with specific protein receptor congenerous; with this steroid.

It is not established yet how do sex hormones enter the target- cells. Partially is important a simple diffusion due to positive gradient of concentration. However, this is not main way of entering. There was obtained data about mechanisms of specific transportation of steroid hormones into prostate gland cells.

With the help of mechanism, which is based on binding steroids with surface of specific carrier, testosterone may be transported against gradient of concentration in higher amounts than are usually found in male blood. A binded steroid penetrates from cytoplasm in nucleus where it reacts with chromatin and DNA, induces synthesis of messenger RNA and amenable ferment proteins responsable for hormone properties.