Up to present, scientists have not found yet causes of prostate cancer. They do study intensively the molecular mechanisms of development and progression of this disease. There was found a gene responsible for family cancer cases, or, in other words, particular genetic predisposition for prostate cancer. There were proved theories that in human genome do exist several areas responsible for inhibition of prostate cancer development and their change results in appearing of this disease.
Some growth factors and biologically active substances have an impact on the disease development including formation of metastasis.
Precancerous changes come before prostate cancer. It is considered they may occur as a result of lasting inflammatory processes having corresponding genetic predisposition.
Risk factors for prostate cancer development:
1) Age is major risk factor. The more older male is, more higher risk factor of cancer development is.
2) Race. Males of black race get diseased with prostate cancer more often than others. The disease in them is found at late stages.
3) Heredity. Relatives of people diseased with prostate cancer in younger age have more chances to get this disease.
4) Food. Cancer occurs more often in men who consume a lot of fats.
5) Smoking and unhealthy work. Cadmium which was found in tobacco smoke and also in accumulators and welding materials contribute to cancer development.
It was considered before that vasectomy (male sterilization operation) prevents from prostate cancer development, however, this was not confirmed.
Detection of prostate cancer causes aggravates the fact that in about 30% of cases prostate cancer is not showing itself and is just accidental finding in dissection of people died from other causes.
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